OTX2 was expressed inside a subset of cells overlying the NANOG-positive EPI inside the blastocyst cavity (Fig
OTX2 was expressed inside a subset of cells overlying the NANOG-positive EPI inside the blastocyst cavity (Fig.?7C). but encompasses WNT parts and genes associated with trophoblast specification. Sequential activation of GATA6, SOX17 and GATA4 markers of primitive endoderm identity is definitely conserved in primates. Unexpectedly, OTX2 is also associated with primitive endoderm specification in human…