It has been shown that ACL is expressed at relatively high levels in the nucleus and that ACL is important for maintaining global histone acetylation levels (Wellen et al
It has been shown that ACL is expressed at relatively high levels in the nucleus and that ACL is important for maintaining global histone acetylation levels (Wellen et al., 2009). characteristics after their birth and for their entire life. This epigenetic effect can even be transmitted to the next generation because maternal methyl-donor supplementation induces…